DP Biology (first assessment 2025)
Question 22M.2.SL.TZ1.4b
| Date | May 2022 | Marks available | [Maximum mark: 3] | Reference code | 22M.2.SL.TZ1.4b | 
| Level | SL | Paper | 2 | Time zone | TZ1 | 
| Command term | Explain | Question number | b | Adapted from | N/A | 
b.
[Maximum mark: 3]
22M.2.SL.TZ1.4b
(b)
Explain the reasons for none of the females in the pedigree chart having hemophilia.
[3]
Markscheme
- hemophilia is X-linked/sex-linked/carried on the X chromosome;
- females have two X chromosomes 
 OR
 males only have one X chromosome;
- hemophilia is caused by a recessive allele;
- (trait) must be on both alleles to be expressed 
 OR
 females would require the allele on both X chromosomes to have the disease
 OR
 females can be carriers when allele is only on one chromosome;
Examiners report
There were many good answers for this question showing understanding of haemophilia being sex linked and recessive Quite a number then failed to get the third mark by being too vague in their explanations. Some candidates thought that hemophilia is carried on Y chromosome; many understand that females have two X chromosomes; talk about females as carriers was often seen, but without any details to expand the answer; or that males are most likely to have hemophilia but, again, no details; for the most part answers showed shallow understanding.
 
